During her studies at the Musik Akademie Basel, Sylvia Nopper became very quickly a much sought-after interpreter for contemporary music. Many of the more than 150 works she has premiered were written especially for her, among them many works for the stage, which had sparked off her enthusiasm for music theatre and contemporary opera. Above all she has a special love for chamber music and all kinds of Lieder, chansons, songs or madrigals. 

Sylvia Nopper works together with composers and conductors such as Heinz Holliger, Jürg Wyttenbach Susanna Mälkki or Pierre Boulez, and has participated in festivals all over the world together with noted orchestras and ensembles like Ensemble Modern Frankfurt, Ensemble Intercontemporain Paris, Klangforum Wien, Phoenix Basel, Contrechamps Genève or Swiss Chamber Soloists. Numerous radio- and CD-recordings document her passion to challenge supposed limits of expression and to explore and open up unknown musical realms.